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Cycloheximide Derivatives from the Fruits of Dipteronia dyeriana

✍ Scribed by Ya-Na Shi; Yi-Ping Zhou; Chun-Lin Long; Ma-Lin Li; Yue-Hu Wang; Xing-Yu Li; Rong Guo; Hong-Sheng Wang

Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
163 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

The phytochemical investigation of Dipteronia dyeriana (Aceraceae) resulted in the isolation and identification of three new cycloheximide derivatives: dipteronines A–C (1–3). Their structures were elucidated based on the 1D‐ and 2D‐NMR spectra. Dipteronine A (1) is the first example of a 10,11‐secocycloheximide. Cytotoxic and antifungal activities of these isolates were also evaluated.

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