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Cyclodextrins as solubilizers: Formation of complex aggregates

โœ Scribed by Jansook, Phatsawee (author);Kurkov, Sergey V. (author);Loftsson, Thorsteinn (author)

Publisher
John Wiley and Sons Inc.
Year
2010
Tongue
English
Weight
321 KB
Volume
99
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES

Cyclodextrins as solubilizers: Formation
Cyclodextrins as solubilizers: Formation of complex aggregates
โœ Jansook, Phatsawee (author);Kurkov, Sergey V. (author);Loftsson, Thorsteinn (aut ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 321 KB

Three different techniques were applied to investigate aggregation of drug/ cyclodextrin complexes, that is, drug permeation through semi-permeable membranes, determination of changes in the value of activity coefficients of drug/cyclodextrin complex solutions and transmission electron microscopy (T

Solubilization and dissolution of tamoxi
Solubilization and dissolution of tamoxifen-hydroxybutenyl cyclodextrin complexes
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The solubility and dissolution of tamoxifen base and tamoxifen citrate with and without hydroxybutenyl-beta-cyclodextrin (HBenBCD) in aqueous and organic media were examined. The solubility of tamoxifen was greatly enhanced by complexation with HBenBCD; pH of the medium, and choice of buffer signifi