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Solubilization of nicardipine hydrochloride via complexation and salt formation

✍ Scribed by Michael B. Maurin; Susan M. Rowe; Christopher A. Koval; Munir A. Hussain

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
325 KB
Volume
83
Category
Article
ISSN
0022-3549

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## Abstract The formation of electrostatic complexes between sodium caseinate and gum arabic (GA) was studied as a function of pH (2.0–7.0), using slow acidification in situ with glucono‐δ‐lactone (GDL) or titration with HCl. The colloidal behavior of the complexes under specific conditions was inv