Cyclodextrin catalysis in the intramolecular Diels-Alder reaction with the furan diene
โ Scribed by Sternbach, Daniel D.; Rossana, Debby M.
- Book ID
- 120945617
- Publisher
- American Chemical Society
- Year
- 1982
- Tongue
- English
- Weight
- 292 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
A variety of substituted furans a-6J undergo the intramolecular Die&Alder reaction at high pressure (12.5 kbar) to provide oxatricyclo adducts Q-12) within 24 hours at room temperature.
An internal Diels-Alder reaction, using furan as the diene component, formed a highly functionalized 5-membered carbocycllc ring in excellent yield. Solvent and substituent effects of this reaction were examined. In connection with a proJect devoted to the synthesis of some natural products contai
Depending on the reaction conditions the intramolecular Diels-Alder reaction of furan-diene 14 yields predominantly either one of two adducts 16a and 16b , which possess the necessary --functionality for eventual transformation into corticosteroids. The dienophile was intro-