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Cyclodextrin-based nanosponges: a propitious platform for enhancing drug delivery

✍ Scribed by Chilajwar, Sai V; Pednekar, Priti P; Jadhav, Kisan R; Gupta, Gajendra JC; Kadam, Vilasrao J


Book ID
121654880
Publisher
Informa plc
Year
2013
Tongue
English
Weight
512 KB
Volume
11
Category
Article
ISSN
1742-5247

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Gelatin-based hydrogels with Ξ²-cyclodext
✍ Liu, Chengde; Zhang, Zhongxing; Liu, Xiao; Ni, Xiping; Li, Jun πŸ“‚ Article πŸ“… 2013 πŸ› The Royal Society of Chemistry 🌐 English βš– 780 KB

In this paper, we demonstrate a simple and practical method to prepare chemically crosslinked gelatinbased hydrogels using b-cyclodextrin (b-CD) that plays a dual role as a crosslinker as well as a host molecule for enhanced binding of anticancer drug methotrexate (MTX), to achieve high drug loading