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Gelatin-based hydrogels with β-cyclodextrin as a dual functional component for enhanced drug loading and controlled release

✍ Scribed by Liu, Chengde; Zhang, Zhongxing; Liu, Xiao; Ni, Xiping; Li, Jun

Book ID
125490822
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
780 KB
Volume
3
Category
Article
ISSN
2046-2069

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Gelatin-based hydrogels with β-cyclodext
Gelatin-based hydrogels with β-cyclodextrin as a dual functional component for enhanced drug loading and controlled release
✍ Liu, Chengde; Zhang, Zhongxing; Liu, Xiao; Ni, Xiping; Li, Jun 📂 Article 📅 2013 🏛 The Royal Society of Chemistry 🌐 English ⚖ 780 KB

In this paper, we demonstrate a simple and practical method to prepare chemically crosslinked gelatinbased hydrogels using b-cyclodextrin (b-CD) that plays a dual role as a crosslinker as well as a host molecule for enhanced binding of anticancer drug methotrexate (MTX), to achieve high drug loading