Cyclodehydration of 4-[(Carboxymethyl)amino]pyridin-2-ones. A New, Efficient Synthesis of Pyrrolo[3,2-c]pyridin-4-ones and Pyrido[3,4-b]pyrrolizidin-1-ones
โ Scribed by Eric D. Edstrom; Tao Yu
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 300 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Acetylation and benzoylation of oxazolo[4,5-b]pyridin-2(3H)-ones, 2-phenyloxazolo-[4,5-b]pyridines and pyrrolo[2,3-b]pyridin-2(2H)-ones were realised via reactions catalyzed with palladium.
## Abstract The title compounds 5aโc and 7aโm have been prepared by Vilsmeier formylation of 4โaminocoumarins 1 yielding aldehydes 2, and subsequent condensation of 2 with CโH acids in the presence of piperidine. This condensation probably proceeds via the intermediate ylidenemalonic esters 4. By m
## Abstract We report the condensation of substituted 2โaminopyridines 5 with ฮฒโketocarboxylic esters in polyphosphoric acid. In this reaction were obtained together with the target compounds, 4__H__โpyrido[1,2โ__a__]pyrirnidinโ4โones 6 also the pyridinโ2โones 7. All the compounds 7 were tested for