Cycloaddition reactions of 1-tert-butyl-4-vinylpyrazole
✍ Scribed by José Sepúlveda-Arques; Mercedes Medio-Simón; Lourdes Piqueres-Vidal
- Publisher
- Springer Vienna
- Year
- 1989
- Tongue
- English
- Weight
- 349 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0026-9247
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📜 SIMILAR VOLUMES
In the title compound, C 20 H 24 , the central cyclohexene ring is in a distorted half-chair conformation. The crystal structure is stabilized by weak van der Waals interactions.
The axial C-Se bond of seleno-and mixed selenoacetak derivedfrom I-tert-butyl cyc2ohexanones exhibit a high tendency to be cleaved by n-butyllithium. The resulting 1 -selerw+tert-butyl cyclohexyllithium are selective& protonated or seIenyIated via axial attack. We recently described 1 that l,l-bis@
trrf-Butyl and 2,6-di(tert-butyl)-4-methylphenyl (RHT) cyclopropanecarboxylates (4, 6, 24, 25) are lithiated with LiN(i-Pr), and t -BuLi, respectively. Reactions with alkyl halides, aldehydes, acyl chlorides, and heteroelectrophiles give a-substituted BHT esters which can be cleaved (t-BuOK/H,O/THF)