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Cycloaddition of diazoacetic ester to 16-dehydropregnenolone acetate under high pressure

✍ Scribed by A. V. Kamernitskii; T. N. Galakhova; I. S. Levina; B. S. Él'yanov


Book ID
112438557
Publisher
Springer
Year
1977
Tongue
English
Weight
294 KB
Volume
26
Category
Article
ISSN
1573-9171

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Regio- and stereoselective thermal cyclo
✍ Navdeep K. Girdhar; M.P.S. Ishar 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 81 KB

Thermal cycloaddition of a-aryl-N-phenylnitrones to the C16 C17 p-bond in 16-dehydropregnenolone-3b-acetate (1) involves only the minor rotamer (E-form) of the nitrones and occurs regio-, stereo-and p-facial-selectively to afford steroido [16,17-d]isoxazolidines (3) in high yield.