Cyclization of N-[2-(l-cyclohexen-l-yl)ethyl] aralkylamides. Synthesis of 1,2,3,4,5,6,7,8-0ctahydroisoquinolines and 1 -oxa-3-azaspiro [5.5] undec-2-enes
✍ Scribed by Raymond R. Wittekind; Sam Lazarus
- Book ID
- 112122913
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1973
- Tongue
- English
- Weight
- 407 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Cyclization of ethyl (__E__)/(__Z__)‐[2‐(1‐cyclohexen‐1‐yl)cyclohexylidene]cyanoacetate (2) in cold concentrated sulfuric acid affords 10‐amino‐1,2,3,4,5,6,7,8‐octahydrophenanthrene‐9‐carboxylic acid (4) and 3,5,6,7,8,8a‐hexahydro‐3‐oxospiro‐[1__H__‐2‐benzopyran‐1,1′‐cyclohexane]‐4‐carb
## Abstract 5′‐Mercapto‐1′__H__‐1,2,4‐triazol‐3′‐yl‐isoquinolinium salts **(6)** were synthesised by the reaction of __ortho__‐acyl phenylacetones **(2)** or the corresponding pyrylium salts **(3)** and 5‐amino‐2,3‐dihydro‐1__H__‐1,2,4‐triazole‐3‐thione **(5)**. Treatment of thioles **6** withα,ω‐d