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Cyclization of anthranilamide-acetylenedicarboxylate adducts. A facile synthesis of 1,4-benzodiazepine-3,5-diones

โœ Scribed by Heindel, Ned D.; Fish, Velmer B.; Lemke, Thomas F.

Book ID
120038581
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
1017 KB
Volume
33
Category
Article
ISSN
0022-3263

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## Abstract magnified image A series of 4โ€methoxycarbonylisoquinolineโ€1,3โ€diones was obtained from homophthalic acid in four steps. The key step was the quantitative and rapid alkaline cyclization of 2โ€methoxycarbonylโ€2โ€(2โ€methoxycarbonylphenyl) acetamides. Homologation easily afforded in the same