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Cyclin-dependent kinase 11p110 activity in the absence of CK2

✍ Scribed by Nancy A Sachs; Richard R Vaillancourt


Book ID
116271148
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
646 KB
Volume
1624
Category
Article
ISSN
0304-4165

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## Abstract Cyclin‐dependent kinase 5 (Cdk5)‐p35 is downregulated in cultured neurons by __N__‐methyl‐d‐aspartate (NMDA) via the proteasomal degradation of p35. However, it is not known where in neurons this downregulation occurs or the physiologic meaning of the reaction. We show the enrichment of