Cyclic GMP: Synthesis, Metabolism, and Function

✍ Scribed by Ferid Murad (Eds.)

Publisher: Academic Press
Year: 1994
Tongue: English
Leaves: 353
Series: Advances in Pharmacology 26
Edition: 1st
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed.

✦ Table of Contents

Content:
Advisory Board
Page ii

Edited By
Page iii

Copyright Page
Page iv

Contributors
Pages xiii-xiv

Preface
Pages xv-xvi
Ferid Murad

Introduction and Some Historical Comments Original Research Article
Pages 1-5
Ferid Murad

Cloning of Guonylyl Cyclase Isoforms Original Research Article
Pages 7-18
Masaki Nakane, Ferid Murad

Regulation of Cytosolic Guanylyl Cyclase by Nitric Oxide: The NO-Cyclic GMP Signal Transduction System Original Research Article
Pages 19-33
Ferid Murad

Regulation of Cytosolic Guanylyl Cyclase by Porphyrins and Metalloporphyrins Original Research Article
Pages 35-65
Louis J. Ignarro

Regulation of Particulate Guonylate Cyclase by Notriuretic Peptides and Escherichia coli Heat-Stable Enterotoxin Original Research Article
Pages 67-86
Dale C. Leitman, Scott A. Waldman, Ferid Murad

Cyclic GMP and Regulation of Cyclic Nucleotide Hydrolysis Original Research Article
Pages 87-114
William K. Sonnenburg, Joseph A. Beavo

Progress in Understanding the Mechanism and Function of Cyclic GhAP-Dependent Protein Kinase Original Research Article
Pages 115-170
Sharron H. Francis, Jackie D. Corbin

Effects of Cyclic GMP on Smooth Muscle Relaxation Original Research Article
Pages 171-194
Timothy D. Warner, Jane A. Mitchell, Hong Sheng, Ferid Murad

Interrelationships of Cyclic GMP, Inositol Phosphates, and Calcium Original Research Article
Pages 195-216
Masato Hirata, Ferid Murad

Cyclic GMP Regulation of Calcium Slow Channels in Cardiac Muscle and Vascular Smooth Muscle Cells Original Research Article
Pages 217-252
Nicholas Sperelakis, Noritsugu Tohse, Yusuke Ohya, Hiroshi Masuda

Effect of Cyclic GMP on Intestinal Transport Original Research Article
Pages 253-283
Arie B. Vaandrager, Hugo R.De Jonge

Cyclic GMP in Lower Forms Original Research Article
Pages 285-303
Joachim E. Schultz, Susanne Klumpp

Clinical Relationships of Cyclic GMP Original Research Article
Pages 305-319
Jean R. Cusson, Johanne Tremblay, Pierre Larochelle, Ernesto L. Schiffrin, Jolanta Gutkowska, Pavel Hamet

Future Directions Original Research Article
Pages 321-324
Ferid Murad

Index
Pages 325-330

Contents of Previous Volumes
Pages 331-335

📜 SIMILAR VOLUMES

Guanylate Cyclase and Cyclic GMP: Method

📁 Guanylate Cyclase and Cyclic GMP: Methods and Protocols

✍ Michael Russwurm, Corina Russwurm, Doris Koesling (auth.), Thomas Krieg, Robert 📂 Library 📅 2013 🏛 Humana Press 🌐 English

<p><p>Recently, many ground-breaking steps have been made towards better understanding NO/cGMP/PKG pathways, its components, substrates, and their localization within a given cell. These advances were only possible due to the development of sophisticated new techniques in the field. In <i>Guanylate

Cyclic ADP-Ribose and NAADP: Structures,

📁 Cyclic ADP-Ribose and NAADP: Structures, Metabolism and Functions

✍ Hon Cheung Lee (auth.), Hon Cheung Lee (eds.) 📂 Library 📅 2002 🏛 Springer US 🌐 English

<p>In the past decade we have witnessed the birth and maturing of a field of research centering on the Ca2+ signaling functions of cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP), which structures and mechanisms of action are truly unique among all Ca2+ messengers

Topological Polymer Chemistry: Progress

📁 Topological Polymer Chemistry: Progress Of Cyclic Polymer In Syntheses, Properties And Functions : Progress of Cyclic Polymers in Syntheses, Properties and Functions

✍ Yasuyuki Tezuka 📂 Library 📅 2012 🏛 World Scientific Publishing Company 🌐 English

There are examples aplenty in the macroscopic world that demonstrate the form of objects directing their functions and properties. On the other hand, the fabrication of extremely small objects having precisely defined structures has only recently become an attractive challenge, which is now opening

📁 Metabolism and Function

📂 Library 🌐 English

Calcium Regulating Hormones, Vitamin D M

📁 Calcium Regulating Hormones, Vitamin D Metabolites, and Cyclic AMP Assays and Their Clinical Application

✍ E. Blind, D. Flentje, S. Fischer (auth.), Professor Dr. med. Heinrich Schmidt-Ga 📂 Library 📅 1990 🏛 Springer-Verlag Berlin Heidelberg 🌐 English

Calcium metabolism is regulated by three specific hormones: parathor- mone, calciferol metabolites, and calcitonin. Cyclic AMP also plays an important part in calcium regulation, and its concentration in urine can be taken as a measure of parathyroid function. Methods for quantitative measurement of

Calcium Regulating Hormones, Vitamin D M

📁 Calcium Regulating Hormones, Vitamin D Metabolites, and Cyclic AMP Assays and Their Clinical Application

✍ Armbruster, Franz Paul;Schmidt-Gayk, Heinrich;Bouillon, Roger 📂 Library 📅 1990 🏛 Springer Berlin Heidelberg 🌐 English

1 Introduction -- 1.1 Clinical Application of Intact Parathyroid Hormone Determination -- 1.2 Clinical Use of Vitamin D Metabolite Assays (Calcidiol and Calcitriol) -- 1.3 Diagnostic Value of the Peptides from the Calcitonin Gene -- 1.4 Immunoassay Vial for Improved Assay Performance -- 2 Parathyroi