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Cyclic AMP regulation of active chloride transport in the rectal gland of marine elasmobranchs

✍ Scribed by Stoff, Jeffrey S. ;Silva, Patricio ;Field, Michael ;Forrest, John ;Stevens, Arthur ;Epstein, Franklin H.

Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 551 KB
Volume: 199
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1401990319

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Active transport of chloride in the salt secreting rectal gland of the dogfish Squalus acanthias is markedly stimulated by the addition of theophylline (0.01 to 5 mM) or dibutyryl cyclic AMP (0.05 mM) during in vitro perfusion. The effect occurs promptly and may persist for two hours. Specific hormonal effectors have not yet been identified. The isolated perfused rectal gland thus offers a unique opportunity to examine the cellular mechanisms of active chloride secretion.

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