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Cyclic AMP Induces Ryanodine-Sensitive Ca2+Release from Microsomal Vesicles of Rat Parotid Acinar Cells

✍ Scribed by Terutaka Ozawa

Book ID
115582090
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
117 KB
Volume
246
Category
Article
ISSN
0006-291X

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Characterization of two different Ca2+up
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We have examined the effect of the Ca2+ (Mg2+)-ATPase inhibitors thapsigargin (TG) and vanadate on ATP-dependent 45Ca2+ uptake into IP3-sensitive Ca2+ pools in isolated microsomes from rat pancreatic acinar cells. The inhibitory effect of TG was biphasic. About 40-50% of total Ca2+ uptake was inhibi