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Cyanoalkylation. II. The Addition of Mercaptans to 1-Cyano-1-cyclohexene

โœ Scribed by Ross, Robert M.; Raths, Fred W.


Book ID
127303929
Publisher
American Chemical Society
Year
1951
Tongue
English
Weight
236 KB
Volume
73
Category
Article
ISSN
0002-7863

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Alkaloid catalyzed asymmetric synthesis
โœ R. Helder; R. Arends; W. Bolt; H. Hiemstra; Hans Wynberg ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 117 KB

The addition of mercaptans to a,B-unsaturated systems is an important reaction in biosynthetic processes2 as well as in synthesis.3 We wish to report the formation in excellent yields of a series of B-ketosulfides in enantiomeric excess up to 50% by the addition of mercaptans to 2-cyclohexene-l-one