Cyanide as a copper-directed inhibitor of amine oxidases: implications for the mechanism of amine oxidation

Cyanide as a copper and quinone-directed

Cyanide as a copper and quinone-directed inhibitor of amine oxidases from pea seedlings (Pisum sativum) andArthrobacter globiformis: evidence for both copper coordination and cyanohydrin derivatization of the quinone cofactor

✍ EricM. Shepard; GregoryA. Juda; Ke-Qing Ling; LawrenceM. Sayre; DavidM. Dooley 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 515 KB

Cyanide as a copper and quinone-directed

Cyanide as a copper and quinone-directed inhibitor of amine oxidases from pea seedlings (Pisum sativum) andArthrobacter globiformis: evidence for both copper coordination and cyanohydrin derivatization of the quinone cofactor

✍ EricM. Shepard; GregoryA. Juda; Ke-Qing Ling; LawrenceM. Sayre; DavidM. Dooley 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

The structure of amine oxidase from E. c

The structure of amine oxidase from E. coli: Implications for the catalytic mechanism

✍ M. Convery; P.F. Knowles; M.J. McPherson; M.R. Parsons; S.E.V. Phillips; K.D.S. 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 62 KB

A comparison of the mechanism for the re

A comparison of the mechanism for the reductive half-reaction between pea seedling and other copper amine oxidases (CAOs)

✍ Rajeev Prabhakar; Per E. M. Siegbahn 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

## Abstract In a previous DFT study a mechanism for the reductive half‐reaction of pea seedling amine oxidase (PSAO) was suggested. In many of the suggested steps a lysine at the active site plays an important role. However, this lysine is not found in other amine oxidases. The primary aim of the p

Oxidation of kynuramine by lentil seedli

Oxidation of kynuramine by lentil seedling copper amine oxidase: demonstration of a single turnover mechanism in the apoenzyme

✍ Alessandra Padiglia; Rosaria Medda; Anita Lorrai; Donatella Congiu; Jens Z. Pede 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 85 KB

Copper amine oxidase was shown to be able to oxidize kynuramine to the corresponding aldehyde, which spontaneously rearranged to 4-hydroxyquinoline. Under anaerobic conditions, the native enzyme oxidized one equivalent of kynuramine and released one equivalent of aldehyde per enzyme subunit. The apo

A Spectrophotometric Method for Determin

A Spectrophotometric Method for Determining the Oxidative Deamination of Methylamine by the Amine Oxidases

✍ José M. Lizcano; Mercedes Unzeta; Keith F. Tipton 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 63 KB

Previously published studies on the oxidative deamination of methylamine by the amine oxidases have determined the formation of radioactively labeled formaldehyde from [(14)C]methylamine. The present work describes a coupled spectrophotometric assay, using formaldehyde dehydrogenase, for the continu