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CXCR6: The Role of Environment in Tumor Progression. Challenges for Therapy

✍ Scribed by Caterina A. M. La Porta


Book ID
111886494
Publisher
Humana Press Inc
Year
2012
Tongue
English
Weight
209 KB
Volume
8
Category
Article
ISSN
1550-8943

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Thrombospondin (TSP-1) is a large glycoprotein secreted by platelets and synthesized by many cell types, including endothelial and tumor cells. Although controversy exists about the biological function of TSP-1, the following observations suggest that TSP-1 may potentiate tumor progression. (1) Tumo