Cutting Edge: Heat Shock Protein 60 Is a
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Ohashi, K.; Burkart, V.; Flohe, S.; Kolb, H.
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Article
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2000
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American Association of Immunologists
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English
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## Abstract Human heat shock protein 60 (hsp60) elicits a potent proinflammatory response in cells of the innate immune system and therefore has been proposed as a danger signal of stressed or damaged cells. We report here that macrophages of C3H/HeJ mice, carrying a mutant Toll-like-receptor (Tlr)