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Current understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme

✍ Scribed by England, Bryant; Huang, Tiangui; Karsy, Michael

Book ID: 120406854
Publisher: S. Karger AG
Year: 2013
Tongue: English
Weight: 342 KB
Volume: 34
Category: Article
ISSN: 1010-4283
DOI: 10.1007/s13277-013-0871-3

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## Abstract Drug resistance remains a key obstacle to successful cancer treatment. The implementation of pharmacogenomics is widely proclaimed as a route to revolutionize the face of cancer therapy. Here we discuss the pharmacogenomics of the p53 tumor suppressor and its role in cancer chemosensiti