๐”– Bobbio Scriptorium
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Current trends in the estimation of Michaelis-Menten parameters

โœ Scribed by G.L. Atkins; I.A. Nimmo


Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
732 KB
Volume
104
Category
Article
ISSN
0003-2697

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โœ H. A. Semple; Dr. Y. K. Tam; R. T. Coutts ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 744 KB

A physiological model of propranolol disposition was designed to help explain the large increase in AUC seen when the drug is administered with food. The mass balance equation for the liver compartment used Michaelis-Menten terms to describe hepatic metabolism. Previously published pharmacokinetic a