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Curcumin Stability and Its Effect on Glutathione S-Transferase P1-1 mRNA Expression in K562 Cells

✍ Scribed by ROMAIN BLASIUS; ANNELYSE DUVOIX; FRANCK MORCEAU; MICHAËL SCHNEKENBURGER; SYLVIE DELHALLE; ESTELLE HENRY; MARIO DICATO; MARC DIEDERICH


Book ID
111478966
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
152 KB
Volume
1030
Category
Article
ISSN
0890-6564

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## Abstract Carcinogenic polycyclic aromatic hydrocarbons(a) form DNA adducts via a complex metabolic activation pathway that includes cytochrome P450(a) 1A1, whereas intermediate metabolites can be detoxified by conjugation through pathways including glutathione s‐transferase M1 (GSTM1). PAH‐DNA a