Codon 273 is one of the hot spots of missense mutation of the p53 tumor suppressor gene found in human cancers. We have previously reported that a mutation at codon 273, p53-273L (Arg 3 Leu), suppresses cell growth despite its having no p53-specific transactivation activity. To further elucidate the
✦ LIBER ✦
c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells
✍ Scribed by Gullberg, Urban; León, Javier; Ceballos, Eva; Delgado, M Dolores; Gutierrez, Pilar; Richard, Carlos; Müller, Daniel; Eilers, Martin; Ehinger, Mats
- Book ID
- 110062871
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 397 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0950-9232
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