Synthesis and Biological Evaluation of C
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Lynette B. Overacre; Robert A. Magarian
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Article
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1998
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Elsevier Science
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English
โ 275 KB
In an effort to prepare effective nonsteroidal antiestrogens without intrinsic estrogenicity and with greater antagonism than the triarylethylenes (tamoxifen), four (E)-and (Z)-1,1dichloro-2-phenyl-2-[4-(2-diethylaminoethoxy)phenyl]-3-(4-methoxyphenyl)cyclopropane analogs of the antiestrogen MER 25,