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Cu(OTf)2-catalysed Ritter reaction: efficient synthesis of amides from nitriles and halohydrocarbons in water

✍ Scribed by Qu, Gui-Rong; Song, Yan-Wei; Niu, Hong-Ying; Guo, Hai-Ming; Fossey, John S.

Book ID: 126062932
Publisher: The Royal Society of Chemistry
Year: 2012
Tongue: English
Weight: 290 KB
Volume: 2
Category: Article
ISSN: 2046-2069
DOI: 10.1039/C2RA20941A

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## Abstract Benzoxazole derivatives have been prepared through the reaction of substituted 2‐aminophenols and acyl chlorides in the presence of catalytic amount of In(OTf)~3~ under solvent‐free reaction conditions in good to excellent yields. The method is simple, convenient, environmental‐friendly