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Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia

✍ Scribed by Nguyen Xuan Nhiem; Phan Van Kiem; Chau Van Minh; Ninh Khac Ban; Nguyen Xuan Cuong; Le Minh Ha; Bui Huu Tai; Tran Hong Quang; Nguyen Huu Tung; Young Ho Kim

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 132 KB
Volume: 48
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.2582

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✦ Synopsis

Abstract

The chemical study of Momordica charantia fruits led to the isolation of three new cucurbitane triterpene glycosides, momordicosides U, V, and W (1–3). The structures of these compounds were determined to be (19__R__, 23__R__)‐5β, 19‐epoxy‐19‐methoxycucurbita‐6,24‐diene‐3β, 23‐diol 3‐O‐β‐D‐allopyranoside (1), (23__R__)‐5β, 19‐epoxycucurbita‐6,24‐diene‐3β, 23‐diol 3‐O‐β‐D‐allopyranoside (2), and (19__R__)‐5β, 19‐epoxy‐19,25‐dihydroxycucurbita‐6,23(E)‐diene‐3β‐ol 3‐O‐β‐D‐glucopyranoside (3), by chemical and spectroscopic methods. Copyright © 2010 John Wiley & Sons, Ltd.

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