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Crystallographic Investigation of Several Malignant Hyperthermia and CPVT Mutations in Ryanodine Receptors

โœ Scribed by Kimlicka, Lynn; Van Petegem, Filip


Book ID
122189751
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
38 KB
Volume
100
Category
Article
ISSN
0006-3495

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Ryanodine receptor mutations in malignan
โœ Tommie V. McCarthy; Kathleen A. Quane; Patrick J. Lynch ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 259 KB ๐Ÿ‘ 2 views

Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that manifests in response to anesthetic triggering agents. Central core disease (CCD) is a myopathy closely associated with MH. Both MH and CCD are primarily disorders of calcium regulation in skeletal muscle. The ryanodin