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Crystallization and Preliminary X-ray Diffraction Analysis of the Rab Escort Protein-1 in Complex with Rab Geranylgeranyltransferase

✍ Scribed by Alexey Rak; Reinhard Reents; Olena Pylypenko; Anca Niculae; Vadim Sidorovitch; Nicolas H Thomä; Herbert Waldmann; Ilme Schlichting; Roger S Goody; Kirill Alexandrov

Book ID
115634273
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
191 KB
Volume
136
Category
Article
ISSN
1047-8477

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Crystallization and preliminary X-ray di
Crystallization and preliminary X-ray diffraction analysis of importin-α complexed with NLS peptidomimetics
✍ Marcos R.M. Fontes; Trazel Teh; Ryan D. Riell; Seung Bum Park; Robert F. Standae 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 200 KB

Importin-alpha is the nuclear import receptor that recognizes cargo proteins with nuclear localization sequences (NLSs). The study of NLS peptidomimetics can provide a better understanding of the requirements for the molecular recognition of cargo proteins by importin-alpha, and potentially engender