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Crystallization and preliminary X-ray crystallographic study of the Ras-GTPase-activating domain of human p120GAP

✍ Scribed by Klaus Scheffzek; Alfred Lautwein; Anna Scherer; Sybille Franken; Alfred Wittinghofer

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 91 KB
Volume: 27
Category: Article
ISSN: 0887-3585
DOI: 10.1002/(sici)1097-0134(199702)27:2<315::aid-prot17>3.0.co;2-p

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✦ Synopsis

Ras-GTPase-activating proteins (Ras-GAPs) are important regulators of the biological activity of Ras within the framework of intracellular communication where GTP-bound Ras (Ras:GTP) is a key signal transducing molecule (Trahey and McCormick,

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