Crystal structures of N1, N5-dibenzoyltetrahydro-4-methyl-1, 5-benzodiazepin-2-one (DBTBO) and tetrahydro-4-methyl-1, 5-benzodiazepin-2-one (TBO)
β Scribed by A. Nallini; K. Saraboji; M. N. Ponnuswamy; M. Venkatraj; R. Jeyaraman
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 145 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0232-1300
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Two benzodiazepines, Diazepam and Flunitrazepam, labeled with carbonβ14 in position 5 of the diazepine ring have been synthesized. Use of a condensation between iminochlorides and ^14^Cβbenzonitriles, followed by exhaustive methylation of the resulting quinazolines and hydrolyses is des
An investigation of the molecular dynamics of substituted 1,3,4,5-tetrahydro-2H-l,Ibenzodiazepin-2-0ne derivatives revealed that these molecules adopt cycloheptadiene-like boat conformations. There is an equilibrium between the quasi-axial and the quasiequatorial conformer in which the quasi-axial c
## Abstract The synthesis from carbonβ^14^C dioxide of 1, 3βdihydroβ1βmethylβ7βnitroβ5βphenylβ2Hβ1, 4βbenzodiazepinβ2βoneβ5β^14^C (I) for use in metabolic studies has been described. The synthesis was achieved by the sequence shown in figure 1. The overall yield of labelled nimetazepam (I) was near
## Abstract For Abstract see ChemInform Abstract in Full Text.