Specific binding of non-steroidal anti-i
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Singh, Nagendra ;Jabeen, Talat ;Sharma, Sujata ;Somvanshi, R. K. ;Dey, Sharmisth
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Article
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2006
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International Union of Crystallography
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English
⚖ 493 KB
Type IIA secretory phospholipase A 2 (PLA 2 ) enzymes catalyze the hydrolysis of the sn-2 ester bond of glycerophospholipids to release fatty acids and lysophospholipids. In order to elucidate the role of PLA 2 in inflammatory disorders and to determine the mode of binding of non-steroidal antiinfla