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Cryptic and complex chromosomal rearrangements and the deletion of TP53 gene in a patient with leukemic mantle cell lymphoma

✍ Scribed by Lijun Zhang; Williams F. Kern; Zongxing Yu; John J. Mulvihill; Shibo Li


Book ID
113512949
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
374 KB
Volume
169
Category
Article
ISSN
0165-4608

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## Abstract Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal disorder caused by mutations in DNA mismatch repair (MMR) genes. Tumors of the HNPCC‐spectrum are associated with microsatellite instability (MSI) and loss of MMR protein expression. Lymphomas are not considered to be HNP