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CrxOS maintains the self-renewal capacity of murine embryonic stem cells

✍ Scribed by Ryota Saito; Tokiwa Yamasaki; Yoko Nagai; Jinzhan Wu; Hiroaki Kajiho; Tadashi Yokoi; Eiichiro Noda; Sachiko Nishina; Hitoshi Niwa; Noriyuki Azuma; Toshiaki Katada; Hiroshi Nishina


Book ID
116299279
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
513 KB
Volume
390
Category
Article
ISSN
0006-291X

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## Abstract Mouse embryonic stem (mES) cells are pluripotent cells that can be propagated in vitro with leukemia inhibitory factor (LIF) and serum. Intracellular signaling by LIF is principally mediated by activation of STAT‐3, although additional pathways for self‐renewal have been described. Here