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Crosstalk between epidermal growth factor receptor and P-glycoprotein in actinomycin D-resistant Chinese hamster lung cells

✍ Scribed by Marian B. Meyers; Peter Yu; John Mendelsohn


Book ID
115783572
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
837 KB
Volume
46
Category
Article
ISSN
0006-2952

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## Abstract Prolonged hypoxia induced transient drug resistance in Chinese hamster lung fibroblasts. Previously hypoxic cells were resistant to adriamycin and resistant to etoposide. Complete recovery of etoposide sensitivity was observed following re‐aeration for 24 hr. A change in P‐glycoprotein