The effect of hypoxia on acquired drug r
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R. Kalra; A-M. Jones; J. Kirk; G. E. Adams; I. J. Stratford
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Article
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1993
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John Wiley and Sons
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French
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## Abstract Prolonged hypoxia induced transient drug resistance in Chinese hamster lung fibroblasts. Previously hypoxic cells were resistant to adriamycin and resistant to etoposide. Complete recovery of etoposide sensitivity was observed following reβaeration for 24 hr. A change in Pβglycoprotein