Crossed immunoelectrofocusing of cerebrospinal fluid immunoglobulins
✍ Scribed by Å. Sidén
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 868 KB
- Volume
- 217
- Category
- Article
- ISSN
- 0340-5354
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✦ Synopsis
The combination of the high separation capacity of isoelectric focusing and the specificity of immunoelectrophoresis gives a valuable tool for protein studies. This technic can be applied to immunoglobulin examinations by using KOCN-treated antibodies isoelectric at pH 5 and performing the immunoelectrophoretic procedure at this pH. CSF and serum samples of patients exhibiting CSF immunoglobulin abnormalities and blood-CSF barrier damages were examined by this method.
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