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Cross–Coupling Reactions of Allylic Alcohols in Water

✍ Scribed by Kei Manabe; Kenji Nakada; Naohiro Aoyama; Shū Kobayashi

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
106 KB
Volume
347
Category
Article
ISSN
1615-4150

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✦ Synopsis

Abstract

Palladium–catalyzed cross–coupling reactions of allylic alcohols and arylboronic acids in water are described. The reactions proceeded smoothly in water at reflux using catalytic amounts of [Pd(allyl)Cl]~2~ and PPh~3~. Addition of a catalytic amount of a base allowed the reaction to proceed even at lower temperatures.

📜 SIMILAR VOLUMES

Complex Allylation by the Direct Cross-C
Complex Allylation by the Direct Cross-Coupling of Imines with Unactivated Allylic Alcohols
✍ Masayuki Takahashi; Martin McLaughlin; Glenn C. Micalizio 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 408 KB 👁 1 views

## Abstract **Regioselective, stereoselective**: The convergent coupling of allylic alcohols with imines to deliver stereodefined homoallylic amines is described (see scheme). The process proceeds with net allylic transposition without the intermediacy of allylic organometallic reagents. Two stereo