To elucidate the specificity of anticardiolipin antibodies (aCL) from patients with the antiphospholipid syndrome (APS) to various phospholipids (PLs), DNA, and &-glycoprotein I (&-GPI). Methods. Five monoclonal aCL were established from peripheral blood lymphocytes of 3 patients with the APS. The
✦ LIBER ✦
Cross-Reactive Epitopes on β2-Glycoprotein-I and Saccharomyces cerevisiae in Patients with the Antiphospholipid Syndrome
✍ Scribed by I. KRAUSE; M. BLANK; R. CERVERA; J. FONT; T. MATTHIAS; S. PFEIFFER; I. WIES; A. FRASER; Y. SHOENFELD
- Book ID
- 111484208
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 719 KB
- Volume
- 1108
- Category
- Article
- ISSN
- 0890-6564
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## Objective: To determine the frequency of mutations in the phospholipid binding domain of beta2-glycoprotein i (beta2gpi) in patients with systemic lupus erythematosus (sle) and/or antiphospholipid syndrome (aps), and to analyze the clinical correlations of such mutations with thromboembolic comp