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Cross interaction of β-amyloid peptide and prion protein fragments

✍ Scribed by Lukasz P. Frankiewicz; Karolina Pulka; Andrzej W. Lipkowski; Aleksandra Misicka

Book ID
110562924
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
606 KB
Volume
9
Category
Article
ISSN
1573-3149

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The neurotoxicity of beta-amyloid protein (beta AP) fragments may be a result of their solution conformation, which is very sensitive to solution conditions. In this work we describe NMR and CD studies of the conformation of beta AP(12-28) in lipid (micelle) environments as a function of pH and lipi