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Cross-coupling reactions of alkenylsilanols with fluoroalkylsulfonates: development and optimization of a mild and stereospecific coupling process

✍ Scribed by Scott E. Denmark; Christopher S. Regens


Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
305 KB
Volume
52
Category
Article
ISSN
0040-4039

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TABLE Cross-Coupling Reactions of Acyl Chlorides with Grignard Reagents in the Presence of Fe(acac)3 as a Catalysta. R-C+ 0 3% Fe(acac)3 0 + 'Cl R'MgXb THF R-C< R' Entry R R' Temp Yield in KetoneC % 1 CH3(Ct& CH3 r.t. 84 2 CH3(CH2)4 CH3(C"2)4 r.t. 82 3 CH3 CH3(CH2)8 r.t. 82 4 CH3 CH3(CH2)9 r.t. 80 5