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Cross-Coupling Reaction of α-Chloroketones and Organotin Enolates Catalyzed by Zinc Halides for Synthesis of γ-Diketones.

✍ Scribed by Makoto Yasuda; Shoki Tsuji; Yusuke Shigeyoshi; Akio Baba


Publisher
John Wiley and Sons
Year
2010
Weight
39 KB
Volume
33
Category
Article
ISSN
0931-7597

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A series of α-(fluoro-substituted phenyl)pyridines have been synthesized by means of a palladium-catalyzed cross-coupling reaction between fluoro-substituted phenylboronic acid and 2-bromopyridine or its derivatives. The reactivities of the phenylboronic acids containing di-and tri-fluoro substituen