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Cromakalim, a vasodilator, differentially inhibits Ca2+ currents in NG108-15 neuroblastoma × glioma hybrid cells

✍ Scribed by Yuji Ito; Isamu Miyamori; Takao Matsubara; Ryoyu Takeda; Haruhiro Higashida


Book ID
115923079
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
387 KB
Volume
262
Category
Article
ISSN
0014-5793

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Inhibition of the M current in NG108-15
✍ Sabine Schäfer; Philippe Béhé; Hans Meves 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 934 KB

The M current, IM, a voltage-dependent noninactivating K current, was recorded in NG108-15 neuroblastoma x glioma hybrid cells, using the whole-cell mode of the patch-clamp technique. We studied inhibition of the M current by bradykinin, phorbol dibutyrate (PDBu), an activator of protein kinase C (P