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Crohn's disease-associated Nod2 mutants reduce IL10 transcription

✍ Scribed by Philpott, Dana J; Girardin, Stephen E


Book ID
109921364
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
996 KB
Volume
10
Category
Article
ISSN
1529-2908

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At this moment, few confirmed associations between NOD2 mutations and diseases other than Crohn's disease (CD) and Blau syndrome (BS) have been reported, but research is ongoing in several fields where a genetic susceptibility factor and/or a role for the innate immune system is suspected. Whether t