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Crohn disease: susceptibility and disease heterogeneity revealed by HLA genotyping

✍ Scribed by Maria Luisa Lombardi; Giuseppe Pirozzi; Vincenza Luongo; Ornella Mercuro; Emilio Pace; Giovanna Blanco Del Vecchio; Antonio Cozzolino; Simona Errico; Caterina Fusco; Fabiana Castiglione


Book ID
117414678
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
184 KB
Volume
62
Category
Article
ISSN
0198-8859

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Etiological heterogeneity in Hodgkin's d
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Forty-one multiplex families, from published sources and new data from the National Cancer Institute, segregating for Hodgkin's disease and HLA, have been studied. A reanalysis of these data strongly suggests a recessive mode of inheritance for susceptibility to Hodgkin's disease. The HLA haplotype