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Critical role of T cell migration in bacterial superantigen-mediated shock in mice

โœ Scribed by Hirotsugu Kano; Yasuhiko Ito; Kentaro Matsuoka; Toshiharu Nakajima; Tsutomu Iwata; Takao Kohsaka; Hirohisa Saito; Jun Abe

Book ID
116366108
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
867 KB
Volume
110
Category
Article
ISSN
1090-2341

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## Abstract Although signal pathways triggered __via__ the CD40 molecule are well characterized, those induced __via__ CD154 are less known. This study demonstrates that engagement of CD154 in Jurkat D1.1 cells with soluble CD40 leads to PKC ฮฑ and ฮด activation, calcium mobilization, and phosphoryla