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Cremophor EL affects multidrug resistance. A comparison with cyclosporin A and other resistance modifiers

โœ Scribed by Schuurhuis, G.J.; Broxterman, H.J.; Pinedo, H.M.; van Heijningen, Th.H.M.; van Kalken, C.K.; Vermorken, J.B.; Spoelstra, E.C.; Lankelma, J.


Book ID
122070729
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
118 KB
Volume
17
Category
Article
ISSN
0305-7372

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โœ Fady Daniel; Marie-Anne Loriot; Philippe Seksik; Jacques Cosnes; Jean-Marc Gorne ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 86 KB

Background: Cyclosporine A (CsA) is inconstantly effective in inducing remission in acute attacks of ulcerative colitis (UC) not responding to steroids. This study aimed to establish whether multidrug resistance gene (MDR)1 polymorphisms would be associated with CsA failure. ## Patients and Methods