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Comparison of cyclosporin A and SDZ PSC833 as multidrug-resistance modulators in a daunorubicin-resistant Ehrlich ascites tumor

โœ Scribed by Ellen Friche; Peter Buhl Jensen; Nis I. Nissen


Publisher
Springer
Year
1992
Tongue
English
Weight
379 KB
Volume
30
Category
Article
ISSN
0344-5704

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๐Ÿ“œ SIMILAR VOLUMES


SDZ PSC 833, A non-immunosuppressive cyc
โœ Roland P. Keller; Hans J. Altermatt; Kees Nooter; Guenter Poschmann; Jean A. Lai ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 637 KB

Cyclosporin A (CsA, Sandimmune) is known to reverse P-glycoprotein(P-gp I70)mediated multidrug resistance as efficiently as other prototype compounds of resistance modifiers. The immunosuppressive activity and nephrotoxicity of CsA, however, may limit its clinical use. PSC-833, a new cyclosporine, e