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CREM: A Master-Switch in the Transcriptional Response to cAMP

โœ Scribed by Lamas, M.; Monaco, L.; Zazopoulos, E.; Lalli, E.; Tamai, K.; Penna, L.; Mazzucchelli, C.; Nantel, F.; Foulkes, N. S.; Sassone-Corsi, P.

Book ID
120153181
Publisher
The Royal Society
Year
1996
Tongue
English
Weight
1010 KB
Volume
351
Category
Article
ISSN
0080-4622

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โœ Paolo Sassone-Corsi ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 38 KB ๐Ÿ‘ 1 views

Cyclic AMP-responsive element modulator (CREM) is a transcription factor highly expressed in the post-meiotic germ cells of the testis. Its pivotal role is to regulate the expression of several germ cell-specific genes, a crucial function as demonstrated by the severe phenotype of mice whose CREM ge