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Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2

✍ Scribed by Sandra Goebbels; Ulli Bode; Alexander Pieper; Ursula Funfschilling; Markus H. Schwab; Klaus-Armin Nave


Book ID
102844753
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
529 KB
Volume
42
Category
Article
ISSN
1526-954X

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Inactivation of the murine Transferrin R
✍ Daniel F. Wallace; Ian D. Tonks; Anna Zournazi; Graham F. Kay; V. Nathan Subrama πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 139 KB πŸ‘ 1 views

## Abstract Summary: Transferrin Receptor 2 (TfR2) is a key molecule involved in the regulation of iron homeostasis. Mutations in TfR2 lead to type 3 hemochromatosis in humans. We have developed mice with a targeted deletion of TfR2. The Cre‐recombinase:__lox__P system used to create the mice allow