✦ LIBER ✦

Credit for clinical trial data

Book ID: 118051736
Publisher: Nature Publishing Group
Year: 2012
Tongue: English
Weight: 310 KB
Volume: 44
Category: Article
ISSN: 1061-4036
DOI: 10.1038/ng.2464

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This article presents some real-life challenges faced by clinical trial Data Monitoring Committees (DMCs), with the aim of clarifying some of the controversial issues that relate to both statistical stopping boundaries and DMC decision-making. Specific attention is given to what constitutes a sensib