Current controversies in data monitoring
โ
Pocock, S. J
๐
Article
๐
2006
๐
SAGE Publications
๐
English
โ 502 KB
This article presents some real-life challenges faced by clinical trial Data Monitoring Committees (DMCs), with the aim of clarifying some of the controversial issues that relate to both statistical stopping boundaries and DMC decision-making. Specific attention is given to what constitutes a sensib